| 摘要 |
FIELD: medicine.SUBSTANCE: invention provides a therapeutic composition for treating and relieving diseases and disorders associated with fibrosis, containing: a carrier specified in a group consisting of a non-cationic polymer carrier, a liposomal carrier, a dendritic carrier, a nanomaterial carrier, a biostructural carrier and a micellar carrier; a targeting agent functionally bound to the carrier; the above targeting agent contains retinoid; and a therapeutic agent functionally bound to the carrier; the above therapeutic agent shows the therapeutic activity after the target organ or tissue delivery; the above therapeutic activity is specified in a group consisting of fibrosis inhibition in the above target organ or tissue.EFFECT: higher selectivity and efficacy of the therapeutic agent delivery to the fibrosis involved organ or tissue.39 cl, 10 ex, 9 dwg |
