NOVEL PROCESS FOR THE SYNTHESIS OF 7-CHLORO-4-(PIPERAZIN-1-YL)-QU INOLINE.
摘要
<p>The present invention provides a new process of synthesis of a polymorph of 7-chloro-4-(piperazin-1-yl)-quinoline of Formula I. Said quinoline compound is substantially pure of any impurities. The present invention further provides the use of the above-mentioned polymorph of 7-chloro-4-(piperazin-1-yl)-quinoline in the synthesis of piperaquine or one of its pharmaceutically acceptable salts.</p>
