摘要 |
The invention provides novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies where the compounds having the general formula U1 - M - U2 wherein M is a linking group covalently joining R2, R3, R4 or R5 of U1 to an R2, R3, R4 or R5 group of U2; U1 and U2 have the general formula (I) and G, X1, X2, R2, R3, R3', R4, R4' and R5, are as described herein. |
申请人 |
GENENTECH, INC. |
发明人 |
WANG, LAN;COHEN, FREDERICK;KOEHLER, MICHAEL F. T.;NDUBAKU, CHUDI;DESHAYES, KURT;FLYGARE, JOHN A.;GAZZARD, LEWIS J. |