发明名称 |
SELF COUPLING RECOMBINANT ANTIBODY FUSION PROTEINS |
摘要 |
A compound comprising three components A, B, and C, which components are covalently bound forming the compound having the structure A-B-C wherein component A has a specific binding affinity for antigens, component B is covalently linked to component A component C is a compound having an alkylated purine or pyrimidine moiety such as guanine, cytosine or a Coenzyme A moiety and linked thereto a moiety having a physiological effect with the proviso that component B has an catalytical or acceptor activity to couple component C with covalently coupled components A-B. |
申请公布号 |
US2014023592(A1) |
申请公布日期 |
2014.01.23 |
申请号 |
US201314041966 |
申请日期 |
2013.09.30 |
申请人 |
RWTH AACHEN;FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. |
发明人 |
RIBBERT MARKUS;BARTH STEFAN;KAMPMEIER FLORIAN |
分类号 |
C12N9/10;A61K49/00;C07K14/485;C07K14/705;C07K14/71;C07K16/28;G01N21/64 |
主分类号 |
C12N9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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