发明名称 |
METHODS OF PREPARATION OF CONJUGATES |
摘要 |
The invention relates to novel benzodiazepine derivatives with antiproliferative activity and more specifically to novel benzodiazepine compounds of formula (I)-(VII). The invention also provides conjugates of the benzodiazepine compounds linked to a cell-binding agent. The invention further provides compositions and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the compounds or conjugates of the invention. |
申请公布号 |
KR20140010067(A) |
申请公布日期 |
2014.01.23 |
申请号 |
KR20137023868 |
申请日期 |
2012.02.15 |
申请人 |
IMMUNOGEN, INC. |
发明人 |
FISHKIN NATHAN;MILLER MICHAEL;LI WEI;SINGH RAJEEVA |
分类号 |
C07D487/04;A61K31/5517;A61K47/48;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|