发明名称 TREATMENT FOR CANCER PATIENT BY ADMINISTERING mTOR INHIBITOR
摘要 PROBLEM TO BE SOLVED: To provide a treatment method capable of permitting larger daily doses of an mTOR inhibitor and greater cumulative exposure to the drug than would be preferred on a 7-day/week schedule which is a simple schedule in common use without unduly increasing the risk of mouth sores, especially the risk of more severe grades of such mouth sores, and without impairing a treatment effect using the mTOR inhibitor.SOLUTION: A treatment method comprises a step of administering an mTOR inhibitor such as sirolimus, temsirolimus, everolimus, or AP23573 for four or five consecutive days per week, respectively, to a patient in need for treatment, and for the following three or two days, respectively, without treatment with the mTOR inhibitor.
申请公布号 JP2014012721(A) 申请公布日期 2014.01.23
申请号 JP20130191029 申请日期 2013.09.13
申请人 ARIAD PHARMACEUTICALS INC 发明人 CAMILLE L BEDROSIAN
分类号 A61K45/00;A61K31/436;A61P35/00;A61P35/02;A61P43/00 主分类号 A61K45/00
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