| 摘要 |
PROBLEM TO BE SOLVED: To provide an extract of a fraxinus excelsior seed and therapeutic application therefor.SOLUTION: The extract of a fraxinus excelsior seed that can be administered for therapeutic treatment of a subject, including a human, by blocking fat synthesis, activating PPAR-alpha, increasing hypoglycemic activity, reducing bodyweight, controlling fasting plasma insulin levels against hyperinsulinemia, and promoting insulin sensitivity and causing a beneficial acute insulinotropic effect. The extract of the fraxinus excelsior seed includes, inter alia, an isolated compound such as (2S, 3E, 4S) 2H-Pyran-4-acetic acid-3-ethylidene-2-[(6-O-&bgr;-D-glucopyranosyl-&bgr;-D-glucopyranosyl) oxy]-3,4-dihydro-5-(methoxycarbonyl) methyl ester. |
