发明名称 SOLID FORMS OF (R)-2-(5-(2-(3-ETHYLUREIDO)-6-FLUORO-7-(TETRAHYDROFURAN-2-YL)-1H-BENZO[D]IMIDAZOL-5-YL)PYRIMIDIN-2-YL)PROPAN-2-YL DIHYDROGEN PHOSPHATE AND SALTS THEREOF
摘要 The invention relates to solid forms of the Formula (I) wherein X is -PO(OH)2, -PO(OH)O-M+, or -PO(O-)2s2M+,wherein M is a monovalent cation such as Na+, K+, Li+, or NH4 +. The invention also provides pharmaceutically acceptable compositions comprising the solid form of he compound and method of using the compositions in the treatment of various disorders.
申请公布号 WO2014015105(A1) 申请公布日期 2014.01.23
申请号 WO2013US51008 申请日期 2013.07.18
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 O'DOWD, HARDWIN;MACIKENAS, DAINIUS;SONG, BIN
分类号 C07D405/14;A61K31/506;A61P31/04;C07F9/6558 主分类号 C07D405/14
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