| 摘要 |
PROBLEM TO BE SOLVED: To provide a method of producing optically active trans-2,6-dimethylmorpholine.SOLUTION: A method of producing optically active trans-2,6-dimethylmorpholine comprises steps of: (i) reacting racemic trans-2,6-dimethylmorpholine with D-mandelic acid; (ii) separating a salt, formed from D-mandelic acid and one enantiomer of the trans-2,6-dimethylmorpholine, from the other enantiomer of the trans-2,6-dimethylmorpholine by precipitation and taking out the salt; and (iii) isolating desired optically active trans-2,6-dimethylmorpholine. |
