发明名称 NOVEL OCTAHYDROTHIENOQUINOLINE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING DERIVATIVE, AND USE OF THESE
摘要 The present invention provides compounds represented by the general formula (I): or pharmaceutical acceptable salts thereof, wherein R 1 is cyano or the like; R 2 and R 3 are hydrogen or the like; R 4 is C 1-6 alkyl or the like; R 5 is C 1-6 alkyl, halo-C 1-6 alkyl, cycloalkyl, cycloalkyl-C 1-6 alkyl, aralkyl or the like; R 6 and R 7 are each hydrogen, C 1-6 alkyl, halo-C 1-6 alkyl, cycloalkyl, C 1-6 alkoxy-C 1-6 alkyl, R 12 R 13 N-C 1-6 alkyl or the like, which exhibit potent dopamine D 2 receptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.
申请公布号 EP2687532(A1) 申请公布日期 2014.01.22
申请号 EP20120758328 申请日期 2012.03.12
申请人 KISSEI PHARMACEUTICAL CO., LTD. 发明人 NISHIMURA, Toshihiro;TERANISHI, Hirotaka;YOSHIDA, Masako;UENO, Yasunori;KASAI, Kiyoshi
分类号 C07D495/04;A61K31/4365;A61K31/444;A61K31/4545;A61K31/496;A61K45/00;A61P5/06;A61P9/00;A61P25/16;A61P43/00 主分类号 C07D495/04
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