发明名称 |
NOVEL OCTAHYDROTHIENOQUINOLINE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING DERIVATIVE, AND USE OF THESE |
摘要 |
The present invention provides compounds represented by the general formula (I): or pharmaceutical acceptable salts thereof, wherein R 1 is cyano or the like; R 2 and R 3 are hydrogen or the like; R 4 is C 1-6 alkyl or the like; R 5 is C 1-6 alkyl, halo-C 1-6 alkyl, cycloalkyl, cycloalkyl-C 1-6 alkyl, aralkyl or the like; R 6 and R 7 are each hydrogen, C 1-6 alkyl, halo-C 1-6 alkyl, cycloalkyl, C 1-6 alkoxy-C 1-6 alkyl, R 12 R 13 N-C 1-6 alkyl or the like, which exhibit potent dopamine D 2 receptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof. |
申请公布号 |
EP2687532(A1) |
申请公布日期 |
2014.01.22 |
申请号 |
EP20120758328 |
申请日期 |
2012.03.12 |
申请人 |
KISSEI PHARMACEUTICAL CO., LTD. |
发明人 |
NISHIMURA, Toshihiro;TERANISHI, Hirotaka;YOSHIDA, Masako;UENO, Yasunori;KASAI, Kiyoshi |
分类号 |
C07D495/04;A61K31/4365;A61K31/444;A61K31/4545;A61K31/496;A61K45/00;A61P5/06;A61P9/00;A61P25/16;A61P43/00 |
主分类号 |
C07D495/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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