METHOD FOR CRYSTALLIZATION OF TRX-TXNIP COMPLEX MUTEIN AND 3D STRUCTURE THEREOF

摘要

The present invention relates to TXNIP modified protein; a production method of the TXNIP modified protein; a polynucleotide coding the TXNIP modified protein; an expression vector including the polynucleotide; a transformant in which the expression vector is transduced; a crystallization method for TRX-TXNIP complex modified protein using the TXNIP modified protein; a material controlling the interaction between TRX and TXNIP; and a screening method for a TRX activation inhibitor and a material controlling functions TXNIP.