MONOSUBSTITUTED PIPERAZINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

摘要

Monosubstituted piperazines of the formula: in which: A is -(CH2)n-, n being 1, 2 or 3, or R being alkyl up to C5 inclusive, trifluoromethyl, phenyl, halophenyl, lower-alkylphenyl, lower-alkoxyphenyl or trifluoromethylphenyl and Ar is phenyl, halophenyl, lower-alkylphenyl, lower-alkoxyphenyl, methylenedioxyphenyl, hydroxyphenyl, or in which X is a single bond, oxygen, sulfur or carbonyl and Y is hydrogen, halogen, lower alkyl or lower alkoxy. These compounds and their physiologically tolerable acid addition salts thereof may be used as medicines especially in the treatment of inflammation with immunological component.