发明名称 FC VARIANTS
摘要 Disclosed are Fc-containing proteins comprising a binding region and a variant Fc region that can elicit one or more immune effector function and/or bind to an Fc receptor more effectively than a similar Fc-containing protein comprising a wild type Fc region. Also disclosed are nucleic acids encoding such Fc-containing proteins, methods for making such proteins, and methods of treatment utilizing such proteins.
申请公布号 EP2686345(A1) 申请公布日期 2014.01.22
申请号 EP20120711513 申请日期 2012.03.15
申请人 AMGEN INC. 发明人 LIU, ZHI;KANNAN, GUNASEKARAN;YAN, WEI
分类号 C07K16/00 主分类号 C07K16/00
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