POLYMER HYDROGELS FOR IN VIVO APPLICATIONS AND METHODS FOR USING AND PREPARING SAME
摘要
<p>Compositions and methods are described for a polymer hydrogel created by a cycloaddition reaction between an azide and an alkyne that proceeds rapidly without catalyst to produce the polymer hydrogel in less than ninety seconds. The polymer hydrogel can be used in in vivo applications for the localized delivery of therapeutic agent in aqueous solutions. An example of therapeutic delivery of a protein in a mouse model is demonstrated.</p>
申请公布号
EP2686018(A2)
申请公布日期
2014.01.22
申请号
EP20120757920
申请日期
2012.03.19
申请人
GEORGIA TECH RESEARCH CORPORATION
发明人
MURTHY, NIREN;HERMANN, CHRISTOPHER;WILSON, DAVID SCOTT;NING, XINGHAI;BOYAN, BARBARA D.;SCHWARTZ, ZVI;GULDBERG, ROBERT;DIAB, TAMIM