发明名称 |
Methods for the identification, assessment, and treatment of patients with cancer therapy |
摘要 |
The present invention is directed to the identification of predictive markers that can be used to determine whether patients with cancer are clinically responsive or non-responsive to a therapeutic regimen prior to treatment. In particular, the present invention is directed to the use of certain individual and/or combinations of predictive markers, wherein the expression of the predictive markers correlates with responsiveness or non-responsiveness to a therapeutic regimen. Thus, by examining the expression levels of individual predictive markers and/or predictive markers comprising a marker set, it is possible to determine whether a therapeutic agent, or combination of agents, will be most likely to reduce the growth rate of tumors in a clinical setting. |
申请公布号 |
EP2687608(A1) |
申请公布日期 |
2014.01.22 |
申请号 |
EP20130181515 |
申请日期 |
2006.06.08 |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC. |
发明人 |
BRYANT, BARBARA;DAMOKOSH, ANDREW;MULLIGAN, GEORGE |
分类号 |
C12Q1/68;G06Q50/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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