发明名称 |
Small molecule inhibitors of influenza A RNA-dependent RNA polymerase |
摘要 |
Antiviral compositions and methods are contemplated that are especially effective in the treatment and prevention of influenza A viruses. Also presented are cellular assays to identify small molecule compounds having antiviral properties, particularly as it relates to detection of influenza A RNA-dependent RNA polymerase activity in a mammalian cell independent of other influenza A components. Preferred assays allow for identification of viral replication inhibitors that do not disrupt normal cellular activity. |
申请公布号 |
US8633198(B1) |
申请公布日期 |
2014.01.21 |
申请号 |
US201213622807 |
申请日期 |
2012.09.19 |
申请人 |
NIAZI KAYVAN;RABIZADEH SHAHROOZ;LE NY ANNE-LAURE;BUZKO OLEKSANDR;GOLOVATO JUSTIN;SOON-SHIONG PATRICK;NANT HOLDINGS IP, LLC |
发明人 |
NIAZI KAYVAN;RABIZADEH SHAHROOZ;LE NY ANNE-LAURE;BUZKO OLEKSANDR;GOLOVATO JUSTIN;SOON-SHIONG PATRICK |
分类号 |
A01N43/90;A01N37/18;A61K31/519;A61K38/00;A61P31/12 |
主分类号 |
A01N43/90 |
代理机构 |
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代理人 |
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地址 |
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