发明名称 |
Nitroxyl (HNO) releasing compounds and uses thereof in treating diseases |
摘要 |
Disclosed is a compound of the formula (I) or a pharmaceutically acceptable salt thereof: (I) in which R1, R2, R3, and R4 are defined herein and pharmaceutical compositions thereof. Further provided is a method of treating various disorders, such as a disorder selected from the group consisting of a cardiovascular disorder, cancer, chronic pain, alcohol dependence, and inflammation in a patient comprising administering an effective amount of a compound or pharmaceutically acceptable salt of formula (I). |
申请公布号 |
US8633177(B2) |
申请公布日期 |
2014.01.21 |
申请号 |
US201113582487 |
申请日期 |
2011.03.18 |
申请人 |
MIRANDA KATRINA M.;WINK DAVID A.;SALMON DEBRA J.;BASUDHAR DEBASHREE;KEEFER LARRY K.;SAAVEDRA JOSEPH E.;ANDREI DANIELA;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;THE ARIZONA BOARD OF REGENTS, ON BEHALF OF THE UNIVERSITY OF ARIZONA |
发明人 |
MIRANDA KATRINA M.;WINK DAVID A.;SALMON DEBRA J.;BASUDHAR DEBASHREE;KEEFER LARRY K.;SAAVEDRA JOSEPH E.;ANDREI DANIELA |
分类号 |
A61K31/655;C07C245/24 |
主分类号 |
A61K31/655 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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