发明名称 Nitroxyl (HNO) releasing compounds and uses thereof in treating diseases
摘要 Disclosed is a compound of the formula (I) or a pharmaceutically acceptable salt thereof: (I) in which R1, R2, R3, and R4 are defined herein and pharmaceutical compositions thereof. Further provided is a method of treating various disorders, such as a disorder selected from the group consisting of a cardiovascular disorder, cancer, chronic pain, alcohol dependence, and inflammation in a patient comprising administering an effective amount of a compound or pharmaceutically acceptable salt of formula (I).
申请公布号 US8633177(B2) 申请公布日期 2014.01.21
申请号 US201113582487 申请日期 2011.03.18
申请人 MIRANDA KATRINA M.;WINK DAVID A.;SALMON DEBRA J.;BASUDHAR DEBASHREE;KEEFER LARRY K.;SAAVEDRA JOSEPH E.;ANDREI DANIELA;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;THE ARIZONA BOARD OF REGENTS, ON BEHALF OF THE UNIVERSITY OF ARIZONA 发明人 MIRANDA KATRINA M.;WINK DAVID A.;SALMON DEBRA J.;BASUDHAR DEBASHREE;KEEFER LARRY K.;SAAVEDRA JOSEPH E.;ANDREI DANIELA
分类号 A61K31/655;C07C245/24 主分类号 A61K31/655
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