发明名称 PHARMACEUTICAL COMPOSITION CONTAINING ENZYME RIBONUCLEASE AND GLYCYRRHIZIC ACID OR SALTS THEREOF: AMMONIUM OR DIPOTASSIUM OR TRISODIUM GLYCYRRHIZINATE
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: present invention refers to pharmaceutical industry and represents a composition for treating and preventing viral infections caused by RNA-containing viruses, such as influenza, parainfluenza, parotitis, rubeola viruses, respiratory syncytial virus, rubella virus, rhinovirus, containing an active ingredient in the form of 0.001-0.5 wt % of ribonuclease (RNA-ase) and 0.001-0.5 wt % of glycyrrhizinic acid or a salt thereof: ammonium or dipotassium or trisodium glycyrrhizinate; the carriers are as follows: 0.05-1.0 wt % of a polymer carrier, 0.001-5.0 wt % of ?-cyclodextrins or hydrogenised lecitin and acceptable excipients.EFFECT: invention provides the preserved activity of the enzyme ribonuclease for a longer period of time, the higher stability and potentiated combined antiviral action.1 cl, 9 ex, 3 tbl
申请公布号 RU2504397(C1) 申请公布日期 2014.01.20
申请号 RU20120145621 申请日期 2012.10.25
申请人 KLOPOTENKO LEONID LEONIDOVICH 发明人 KLOPOTENKO LEONID LEONIDOVICH
分类号 A61K38/46;A61K31/704;A61P31/14 主分类号 A61K38/46
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