发明名称 COMPOSITIONS AND METHODS FOR THE PRODUCTION OF PYRIMIDINE AND PYRIDINE COMPOUNDS WITH BTK INHIBITORY ACTIVITY
摘要 <p>The present invention provides novel pyrimidine and pyridine compounds according to Formula (I), Formula (II), Formula (III), Formula (IV) and Formula (V) their manufacture and use for the treatment of hyperproliferative diseases including, but not limited to, cancer, lupus, allergic disorders, Sjogren's disease and rheumatoid arthritis. In preferred embodiments, the present invention describes irreversible kinase inhibitors including, but not limited to, inhibitors of Bruton's tyrosine kinase.</p>
申请公布号 KR20140007954(A) 申请公布日期 2014.01.20
申请号 KR20137032537 申请日期 2012.06.10
申请人 MERCK PATENT GMBH 发明人 HODOUS BRIAN L.;LIU BUJALSKI LESLEY;JONES REINALDO;BANKSTON DONALD;JOHNSON THERESA L.;MOCHALKIN IGOR;NGUYEN NGAN;QIU HUI;GOUTOPOULOS ANDREAS;BRUGGER NADIA
分类号 C07D401/12;A61K31/506;A61P35/00 主分类号 C07D401/12
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