发明名称 INHALATION PREPARATION FOR TREATING BRONCHAIL ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND METHOD FOR PREPARING IT
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: present invention refers to medicine and pharmaceutical industry and describes an inhalation preparation for treating bronchial asthma and chronic obstructive pulmonary disease, containing micronized budesonide and micronised formoterol fumarate dehydrate as active ingredients, wherein the preparation contains a carrier presented by lactose of average particle diameter 1 to 10 mcm and sodium benzoate of bulk density 0.30-0.50 g/cm, in the following proportions of the ingredients per a dose of the preparation: budesonide 50 mcg - 800 mcg, formoterol fumarate dehydrate 4.5 mcg - 18 mcg, lactose 5 mg - 50 mg, sodium benzoate 0.01 mg - 5 mg. What is also described is a method for producing the given preparation.EFFECT: invention provides a higher percentage of a fraction of the active substances and respectively higher effectiveness.4 cl, 8 ex
申请公布号 RU2504382(C1) 申请公布日期 2014.01.20
申请号 RU20120124231 申请日期 2012.06.13
申请人 SHOLEKS DEVELOPMENT GMBKH 发明人 MALIN ALEKSANDR ALEKSANDROVICH;MIKHAJLOV OLEG ROSTISLAVOVICH;UVAROV NIKOLAJ ALEKSANDROVICH
分类号 A61K31/573;A61K9/14;A61K9/72;A61K31/58;A61K47/26;A61P11/00;A61P11/06 主分类号 A61K31/573
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