| 发明名称 |
SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF |
| 摘要 |
The invention provides compounds with enhanced permeability for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc. |
| 申请公布号 |
US2014018309(A1) |
申请公布日期 |
2014.01.16 |
| 申请号 |
US201113997484 |
申请日期 |
2011.12.21 |
| 申请人 |
KAUL RAMESH;MCEACHERN ERNEST J.;MU CHANGWEI;SELNICK HAROLD G.;VOCADLO DAVID J.;WANG YAODE;WEI ZHONGYONG;ZHOU YUANXI;ZHU YONGBAO;MERCK SHARP & DOHME CORP.;ALECTOS THERAPEUTICS, INC. |
发明人 |
KAUL RAMESH;MCEACHERN ERNEST J.;MU CHANGWEI;SELNICK HAROLD G.;VOCADLO DAVID J.;WANG YAODE;WEI ZHONGYONG;ZHOU YUANXI;ZHU YONGBAO |
| 分类号 |
C07H17/00 |
主分类号 |
C07H17/00 |
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