发明名称 USE OF NANODIAMONDS FOR GENERATING FREE RADICALS FOR THERAPEUTIC PURPOSES UNDER RADIATION
摘要 The present invention relates to the use of nanodiamonds as drugs generating free radicals, in particular for treating tumours. The invention is based on generating free radicals on the surface of the nanodiamonds when they are exposed to radiation, for example ionising radiation. In order to increase the effectiveness of the nanodiamonds, same can be complexed with a radiosensitising agent, such as a chemical molecule or an interfering RNA targeting a repairing gene.
申请公布号 WO2014009930(A1) 申请公布日期 2014.01.16
申请号 WO2013IB55766 申请日期 2013.07.12
申请人 COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIESALTERNATIVES 发明人 PETIT, TRISTAN;ARNAULT, JEAN-CHARLES;GIRARD, HUGUES;GRALL, ROMAIN;CHEVILLARD, SYLVIE;DELIC, JOZO
分类号 A61K47/48;A61K9/00;A61K9/51;A61K33/00;A61K41/00;A61K49/00;B82Y5/00 主分类号 A61K47/48
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