发明名称 |
PROCESSES AND COMPOSITIONS FOR METHYLATION-BASED ENRICHMENT OF FETAL NUCLEIC ACID FROM A MATERNAL SAMPLE USEFUL FOR NON-INVASIVE PRENATAL DIAGNOSES |
摘要 |
Provided are compositions and processes that utilize genomic regions that are differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are particularly useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuploidies. |
申请公布号 |
WO2014011928(A1) |
申请公布日期 |
2014.01.16 |
申请号 |
WO2013US50145 |
申请日期 |
2013.07.11 |
申请人 |
SEQUENOM, INC. |
发明人 |
TYNAN, JOHN, ALLEN;HOGG, GRANT;TANG, MENGJIA |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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