发明名称 |
METHODS OF INDUCING ANESTHESIA |
摘要 |
The present invention provides methods for determining the selectivity of an anesthetic for an anesthetic-sensitive receptor by determining the molar water solubility of the anesthetic. The invention further provides methods for modulating the selectivity of an anesthetic for an anesthetic-sensitive receptor by altering or modifying the anesthetic to have higher or lower water solubility. The invention further provides methods of inducing anesthesia in a subject by administering via the respiratory pathways (e.g., via inhalational or pulmonary delivery) an effective amount of an anesthetic compound identified according to the present methods. |
申请公布号 |
US2014018414(A1) |
申请公布日期 |
2014.01.16 |
申请号 |
US201313830907 |
申请日期 |
2013.03.14 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
BROSNAN ROBERT J. |
分类号 |
A61K31/357;A61K31/025;A61K31/045;A61K31/341;A61K31/351 |
主分类号 |
A61K31/357 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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