| 摘要 |
The invention relates to the use of compounds to ameliorate or treat an condition such as a cystic fibrosis, neutropenia or other exemplified conditions. Exemplary compounds that can be used include 3beta-hydroxy-17beta-aminoandrost-5-ene, 3beta-hydroxy-16alpha-fluoro-17beta-aminoandrost-5-ene, 3alpha-hydroxy-16alpha-fluoro-17beta-aminoandrost-5-ene, 3beta-hydroxy-16beta-fluoro-17beta-aminoandrost-5-ene, 1alpha,3beta-dihydroxy-4alpha-fluoroandrost-5-ene-17-one, 1alpha,3beta,17beta-trihydroxy-4alpha-fluoroandrost-5-ene, 1beta,3beta-dihydroxy-6alpha-bromoandrost-5-ene, 1alpha-fluoro-3beta,12alpha-dihydroxyandrost-5-ene-17-one, 1alpha-fluoro-3beta,4alpha-dihydroxyandrost-5-ene and 4alpha-fluoro-3beta,6alpha,17beta-trihydroxyandrostane. |
