<p>The present invention relates to a method for optimizing a risk assessment of pneumonia based on a clinical prediction rule for classifying subjects with pneumonia. The method is based on the determination of the amount of a least one marker selected from the group consisting of a cardiac Troponin, a brain natriuretic peptide, and sFlt-1, and on the comparison of the determined amount(s) to a reference amount. Further envisaged are kits and devices adapted to carry out the said method.</p>
