发明名称 |
A METHOD OF INHIBITING TAU PHOSPHORYLATION |
摘要 |
A method of inhibiting phosphorylation of the tau protein and/or a TLR4-mediated immune response is disclosed. The method contemplates administering to cells in recognized need thereof such as cells of the central nervous system an effective amount of a of a compound or a pharmaceutically acceptable salt thereof that binds to a pentapeptide of filamin A (FLNA) of SEQ ID NO: 1, and contains at least four of the six pharmacophores of FIGS. 35-40. |
申请公布号 |
WO2014011917(A2) |
申请公布日期 |
2014.01.16 |
申请号 |
WO2013US50126 |
申请日期 |
2013.07.11 |
申请人 |
PAIN THERAPEUTICS, INC. |
发明人 |
WANG, HOAU-YAN;BURNS BARBIER, LINDSAY, |
分类号 |
A61K31/04;A61K31/438;A61K31/5375;A61K38/08 |
主分类号 |
A61K31/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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