摘要 |
This disclosure provides anti-human cytomegalovirus antibodies and methods of treatment, prophylaxis, detection, and diagnosis using the same. In another aspect, the disclosure features therapeutic, prophylactic, and/or diagnostic compositions for human cytomegalovirus infection or for a human cytomegalovirus-related disease that include a binding agent (e.g., antibody) or polynucleotide disclosed herein. In some embodiments, the composition is formulated for ocular or topical administration. The compositions can further include one or more human cytomegalovirus-neutralizing antibodies, an intravenous immunoglobulin preparation, and/or one or more antiviral compounds (e.g., ganciclovir, foscamet, cidofovir, or valganciclovir). |
申请人 |
CELL SIGNALING TECHNOLOGY, INC. |
发明人 |
SATO, SHUJI;BEAUSOLEIL, SEAN, ANDRE;CHEUNG, WAN, CHEUNG;POLAKIEWICZ, ROBERTO, D. |