发明名称 |
Serpin fusion polypeptides and methods of use thereof |
摘要 |
<p>This invention relates to molecules, particularly polypeptides, more particularly fusion proteins that include a serpin polypeptide or an amino acid sequence that is derived from a serpin and second polypeptide comprising of at least one the following: an Fc polypeptide or an amino acid sequence that is derived from an Fc polypeptide; a cytokine targeting polypeptide or a sequence derived from a cytokine targeting polypeptide; a WAP domain containing polypeptide or a sequence derived from a WAP containing polypeptide; and an albumin polypeptide or an amino acid sequence that is derived from a serum albumin polypeptide. This invention also relates to methods of using such molecules in a variety of therapeutic and diagnostic indications, as well as methods of producing such molecules.</p> |
申请公布号 |
AU2012275287(A1) |
申请公布日期 |
2014.01.16 |
申请号 |
AU20120275287 |
申请日期 |
2012.06.28 |
申请人 |
INHIBRX LLC |
发明人 |
ECKELMAN, BRENDAN P.;TIMMER, JOHN C.;NGUY, PETER L.;GUENTHER, GRANT B.;DEVERAUX, QUINN |
分类号 |
C07K16/46 |
主分类号 |
C07K16/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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