摘要 |
<p>Constructs, models, and methods to assay candidate therapeutic agents to treat Alzheimer's disease are described herein. In an embodiment, a construct includes a polynucleotide encoding a fusion protein of (a) a chaperone protein or monosaccharide transferase (MST) and (b) a fluorescent protein. In an embodiment, the fusion occurs where at least one exon of a polynucleotide encoding a chaperone protein or MST is followed by a polynucleotide encoding a fluorescent protein.</p> |