发明名称 CELLULAR AND ANIMAL MODELS FOR SCREENING THERAPEUTIC AGENTS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
摘要 <p>Constructs, models, and methods to assay candidate therapeutic agents to treat Alzheimer's disease are described herein. In an embodiment, a construct includes a polynucleotide encoding a fusion protein of (a) a chaperone protein or monosaccharide transferase (MST) and (b) a fluorescent protein. In an embodiment, the fusion occurs where at least one exon of a polynucleotide encoding a chaperone protein or MST is followed by a polynucleotide encoding a fluorescent protein.</p>
申请公布号 WO2014012108(A1) 申请公布日期 2014.01.16
申请号 WO2013US50532 申请日期 2013.07.15
申请人 HOLTZMAN, JORDAN L. 发明人 HOLTZMAN, JORDAN L.
分类号 C12N15/62 主分类号 C12N15/62
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