发明名称 |
INHIBITORS OF PHOSPHODIESTERASE 10 ENZYME |
摘要 |
<p>The present invention relates to novel imidazo[1,2-b]pyridazine and imidazo[1,2-a]-pyrazine derivatives which are inhibitors of the phosphodiesterase 10 enzyme (PDE10) and which may be useful for the treatment or prevention of neurological, psychiatric and metabolic disorders in which the PDE10 enzyme is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, to the use of such compounds or pharmaceutical compositions for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases.</p> |
申请公布号 |
CA2875057(A1) |
申请公布日期 |
2014.01.16 |
申请号 |
CA20132875057 |
申请日期 |
2013.07.08 |
申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
LECLERCQ, LAURENT CHRISTIAN L.;BARTOLOME-NEBREDA, JOSE MANUEL;CONDE-CEIDE, SUSANA;VAN GOOL, MICHIEL LUC MARIA |
分类号 |
A61K31/4985;A61K31/502;A61P3/00;A61P25/00;C07D487/04 |
主分类号 |
A61K31/4985 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|