发明名称 |
EXTENDED RELEASE, ABUSE DETERRENT PHARMACEUTICAL COMPOSITIONS |
摘要 |
The present disclosure provides pharmaceutical compositions comprising at least one active pharmaceutical ingredient or a pharmaceutically acceptable salt thereof, at least one hydrophilic plastomer, optionally at least one hydrophilic elastomer, and at least one deliquescent plasticizer, wherein the pharmaceutical compositions provide extended release of the API and have abuse deterrent properties. Also provided are methods for preparing the pharmaceutical compositions in which the components of the composition are humidified such that the deliquescent plasticizer deliquesces, thereby plasticizing the hydrophilic polymers. |
申请公布号 |
CA2877774(A1) |
申请公布日期 |
2014.01.16 |
申请号 |
CA20132877774 |
申请日期 |
2013.07.11 |
申请人 |
MALLINCKRODT LLC |
发明人 |
GOWER, BRAD L.;CASTANEDA, CARLOS H.;PARK, JAE HAN;HERMAN, CLIFFORD J. |
分类号 |
A61K9/20;A61K31/485 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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