CORE-SHELL CAPSULES AND METHODS FOR ENCAPSULATION INCLUDING DIFFUSION THROUGH SPHERICAL CAPSULE MEMBRANES

摘要

The present invention relates to a method for encapsulation and to capsules that can be obtained by the method. The method is characterized by the step of counter-current, diffusional exchange across the membrane of a capsule-shell. During the exchange, a solid primary core is replaced by a liquid that may comprise an active agent. The method of the invention may also comprise a step of further processing said capsules, in particular in order to adjust or modify the release characteristics and to control the release of the active agent inside the capsules.