| 摘要 |
The present invention is a process for conversion of DELTA 16-steroids (I) <IMAGE> (I) to the corresponding DELTA 17(20)-20-silyl ether (III) <IMAGE> (III) by reaction with (1) a preformed copper hydride or a metal hydride reducing agent in the presence of a copper species and (2) a silylating agent. The DELTA 17(20)-20-silyl ether (III) are useful intermediates in the preparation of steroids useful as pharmaceuticals.
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