发明名称 BIARYL AMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
摘要 Disclosed is a novel biaryl amide derivative represented by formula (1) and having an affinity for the aldosterone receptor; also disclosed is a pharmaceutically acceptable salt thereof. (In the formula, A is any of the groups represented by formula (a); L is -CONH-, etc.; R 1 is a substitutable aminosulfonyl group, etc.; R 2 is a hydrogen atom, etc.; R 3 is a hydrogen atom, etc.; R 4 is a hydrogen atom, a halogen atom, hydroxy group, a substitutable amino group, a substitutable C 1-6 alkoxy group, a substitutable 4- to 7-membered cyclic amino group, etc.; R 5a , R 5b and R 5c are each independently hydrogen atoms, etc.; R 6 is a halogen atom, a cyano group, etc.; R 7 and R 8 are each independently a hydrogen atom, etc.; and m is an integer such as 0.)
申请公布号 EP2594554(A4) 申请公布日期 2014.01.15
申请号 EP20110806765 申请日期 2011.07.12
申请人 DAINIPPON SUMITOMO PHARMA CO., LTD. 发明人 KATAYAMA, SEIJI;HORI, SEIJI;HASEGAWA, FUTOSHI;SUZUKI, KUNIKO
分类号 C07C311/08;A61K31/167;A61K31/18;A61K31/216;A61K31/235;A61K31/277;A61K31/341;A61K31/351;A61K31/381;A61K31/397;A61K31/40;A61K31/4015;A61K31/403;A61K31/407;A61K31/41;A61K31/415;A61K31/4164;A61K31/4196;A61K31/421;A61K31/4245;A61K31/426 主分类号 C07C311/08
代理机构 代理人
主权项
地址