发明名称 |
IN VIVO SELECTION OF THERAPEUTICALLY ACTIVE ANTIBODIES |
摘要 |
The present invention relates to non-invasive methods of in vivo selecting an antibody against a desired target on the surface of a mammalian cell of a subject by applying near-infrared fluorescence imaging (NIRF) as well as uses of NIRF in such methods. In addition, kits for the use in these methods comprising a panel of potentially therapeutic effective fluorescence labeled antibodies and means for NIRF imaging are provided. |
申请公布号 |
EP2683413(A1) |
申请公布日期 |
2014.01.15 |
申请号 |
EP20120711587 |
申请日期 |
2012.03.06 |
申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
DOBOSZ, MICHAEL;SCHEUER, WERNER |
分类号 |
A61K49/00;A61P35/00 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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