发明名称 |
PHARMACEUTICALLY ACCEPTABLE SALT OF (E)-N-[4-[[3-CHLORO-4-(2-PYRIDYLMETHOXY)PHENYL]AMINO]-3-CYANO-7-ETHOXY-6-QUINOLYL]-3-[(2R)-1-METHYLPYRROLIDIN-2-YL]PROP-2-ENAMIDE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF |
摘要 |
<p>Provided as represented by formula (I) is a pharmaceutically acceptable salt of (E)-N-[4-[[3-chloro-4-(2-pyridylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolyl] -3-[(2 R )-1-methylpyrrolidin-2-yl]prop-2-enamide, a preparation method therefor, and a use thereof as a therapeutic agent and especially as a protein kinase inhibitor.</p> |
申请公布号 |
EP2684877(A2) |
申请公布日期 |
2014.01.15 |
申请号 |
EP20120757831 |
申请日期 |
2012.02.10 |
申请人 |
SHANGHAI HENGRUI PHARMACEUTICAL CO. LTD.;JIANGSU HENGRUI MEDICINE CO. LTD. |
发明人 |
LI, XIN;WANG, BIN |
分类号 |
C07D401/14;A61K31/4709;A61P35/00 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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