发明名称 |
Radiofluorinated compounds and their preparation |
摘要 |
The present invention provides a process for [18F]-fluorination of biomolecules containing a primary amino group such as proteins and peptides and in particular of peptides. The invention further provides reagents for this process, in particular 18F-labelled prosthetic groups for use in the preparation as well as non-labelled intermediates useful in the preparation of the [18F]-labelled prosthetic groups. [18F]-labelled compounds useful as radiopharmaceuticals, specifically for use in Positron Emission Tomography (PET) are also provided. |
申请公布号 |
US8629299(B2) |
申请公布日期 |
2014.01.14 |
申请号 |
US201313898131 |
申请日期 |
2013.05.20 |
申请人 |
HAMMERSMITH IMANET LIMITED |
发明人 |
ARSTAD ERIK;GLASER MATTHIAS EBERHARD |
分类号 |
C07C337/00 |
主分类号 |
C07C337/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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