发明名称 |
Use of megalin in urine as marker for detecting renal disorder |
摘要 |
This invention provides a simple means for detecting a renal disorder, a diagnostic marker for a renal disorder that enables prognostic prediction of a renal disorder (e.g., diabetic nephropathy and IgA nephropathy) and evaluation of the degree of nephropathy at the phase of stage-II diabetic nephropathy by measuring the megalin level in urine associated with a renal disorder used for the detection means, and use of such marker. The invention also provides the use of human megalin obtained from the urine sample of a subject as a marker for detecting a renal disorder. |
申请公布号 |
US8628930(B2) |
申请公布日期 |
2014.01.14 |
申请号 |
US201013266397 |
申请日期 |
2010.04.27 |
申请人 |
SAITO AKIHIKO;TOMINO YASUHIKO;ASANUMA KATSUHIKO;OGASAWARA SHINYA;KUROSAWA HIROYUKI;HIRAYAMA YOSHIAKI;NIIGATA UNIVERSITY;JUNTENDO EDUCATION FOUNDATION;DENKA SEIKEN CO., LTD. |
发明人 |
SAITO AKIHIKO;TOMINO YASUHIKO;ASANUMA KATSUHIKO;OGASAWARA SHINYA;KUROSAWA HIROYUKI;HIRAYAMA YOSHIAKI |
分类号 |
G01N33/53 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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