Method of inducing mucosal immune response to antigen with Dioscorea polysaccharides adjuvant

摘要

A method for inducing mucosal immune responses in a subject in need thereof to an antigen includes administering to the subject a vaccine composition including the antigen and a Dioscorea polysaccharides as an adjuvant. Because of the immuomodulatory effect of the Dioscorea polysaccharides, the vaccine composition is further capable of breaking immunological tolerance in the subject.