发明名称 |
CYTOTOXICITETSMEDIERING AF CELLER DER UDVISER OVERFLADEEKSPRESSION AF CD44 |
摘要 |
<p>This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumour cells evidencing surface expression of CD44; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMAB of the instant invention.</p> |
申请公布号 |
DK1989233(T3) |
申请公布日期 |
2014.01.13 |
申请号 |
DK20070701821T |
申请日期 |
2007.02.23 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
YOUNG, DAVID, S., F.;FINDLAY, HELEN, P.;HAHN, SUSAN, E.;CECHETTO, LISA, M.;MCCONKEY, FORTUNATA |
分类号 |
C07K16/28;A61K39/395;A61P35/00 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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