| 摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to novel 5-fluorouracil derivatives of general formula (I) or pharmaceutically acceptable salts thereof. In general formula(I), Rdenotes a hydrogen atom or a protective hydroxy group which is selected from a C-Caliphatic acyl group; C-Calicyclic acyl group; aromatic acyl group which is selected from a benzoyl group or a halogen-benzoyl group, Rdenotes a lower alkoxy-lower alkyl group; X denotes CH or a nitrogen atom and Y denotes a halogen atom.EFFECT: compounds have anti-tumour activity, balanced with toxicity level, and can be used as an active ingredient for producing a drug for treating malignant diseases.11 cl, 4 dwg, 4 tbl, 24 ex |
