发明名称 CRYSTALLINE FORM OF 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUND
摘要 FIELD: chemistry.SUBSTANCE: invention relates to a crystalline form of 4-[2-(2,4,6-trifluorophenoxymethyl)phenyl]piperidine hydrochloride which is characterised by an X-ray powder diffraction profile having diffraction peaks at the following values of 2?: 4.44±0.20, 10.22±0.20, 17.16±0.20 and 21.78±0.20. The present invention also relates to a pharmaceutical composition containing a crystalline form of 4-[2-(2,4,6-trifluorophenoxymethyl)phenyl]piperidine hydrochloride and having norepinephrine and serotonin reuptake inhibitor action, methods of producing said crystalline salt and use of the crystalline salt to treat diseases, e.g., pain syndrome etc.EFFECT: novel crystalline form of a compound which can be used in treating a range of diseases is obtained and described.11 cl, 8 ex, 5 dwg
申请公布号 RU2503662(C2) 申请公布日期 2014.01.10
申请号 RU20110123890 申请日期 2009.11.13
申请人 TEREVANS, INK. 发明人 PATTERSON LORI DZHIN;CHAO ROBERT;RAPTA MIROSLAV
分类号 C07D211/22;A61K31/4409;A61P25/00 主分类号 C07D211/22
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