发明名称 COMPOUNDS HAVING CRTH2 ANTAGONIST ACTIVITY
摘要 FIELD: chemistry.SUBSTANCE: invention relates to a compound of general formulaand a compound of general formula,where W is chlorine or fluorine, Ris phenyl, optionally substituted with one or more halogen substitutes; and Ris C-Calkyl, or pharmaceutically acceptable salts of said compounds. The invention also relates to a method of producing a compound of formula (II), use of compounds I and II to produce a drub for treating or preventing diseases such as asthma, allergic rhinitis and atopic dermatitis. Also described is a method of treating said diseases, as well as a pharmaceutical composition used to treat allergic diseases such as asthma, allergic rhinitis and atopic dermatitis.EFFECT: novel compounds which can be used in treating allergic diseases such as asthma, allergic rhinitis and atopic dermatitis are obtained and described.15 cl, 6 ex, 3 tbl
申请公布号 RU2503672(C2) 申请公布日期 2014.01.10
申请号 RU20100129027 申请日期 2009.01.19
申请人 OKSAGEN LIMITED 发明人 ARMER RICHARD EHDVARD;PETTIFER EHRIK ROJ;VITTAKER MARK;VAJN GREKHAM MAJKL;VAJL DZHULIJA;SHROER FREHNK
分类号 C07D401/06;A61K31/4439;A61P29/00 主分类号 C07D401/06
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