| 摘要 |
FIELD: biotechnologies.SUBSTANCE: invention refers to application of oligopeptide chosen from a group consisting of tripeptide of general formula X-Pro-Tyr (X-P-Y), in which X can be chosen from a group consisting of Ile (I), Val (V), Ala (A), Trp (W), Leu (L), Phe (F), Gly (G), Glu (E) and Asn (N), or peptides including the above tripeptide, in medicine for immunomodulation. Besides, application of the above oligopeptide for production of remedy to be used as an immunomodulator is disclosed. Immunomodulating pharmaceutical composition containing an effective amount of the above oligopeptide, as well as a vaccine containing it are disclosed. Besides, a method for reinforcement of mammal immune system, as well as a method for improvement of immunogenic activity of vaccine composition using the above immunomodulating composition are disclosed. A method providing immunoreactivity to peptide or improvement of peptide immunoreactivity with a peptide compound with the above oligopeptide is disclosed.EFFECT: use of oligopeptides in medicine for immunomodulation.19 cl, 2 dwg, 2 tbl, 2 ex |
