METHOD OF 1-DICYANOGEN-2-(2-CHLORPHENYL)ETHYLENE UTILISATION

摘要

FIELD: chemistry.SUBSTANCE: invention relates to utilisation of irritating toxic substances (irritants) to nontoxic products, able to find practical application in fine organic synthesis, chemistry of physiologically active substances and medical products. Method of 1-dicyanogen-2-(2-chlorphenyl)ethylene utilisation consists in the following: 1-dicyanogen-2-(2-chlorphenyl)ethylene interacts in solvent with 2-chlorine-1-phenylethanol in presence of ammonium acetate with molar ratio equal to 1:1:2, in acetic acid medium at temperature 60°C, formed crude product 2-phenyl-3-chlorine-4(2-chlorphenyl)-5-cyanogen-6-amine-1-pyridine is filtered, washed with cold ethyl alcohol to pH-6?7 and recrystallised from ethyl alcohol with obtaining pure product.EFFECT: invention makes it possible to apply in utilisation available and cheap reagents, carry out reaction under soft conditions with simultaneous application in reaction of two substances, which require utilisation.1 ex