发明名称 COMPOSITION FOR MODULATION OF CELL ADHESION MOLECULE EXPRESSION
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: presented group of inventions refers to immunology and medicine. There are presented compositions containing a digoxin antibody for weakening the action of tumour necrosis factor on a cell adhesion molecule and for weakening the TNF induction of ICAM, VCAM and E-selectin expression in an endothelial cell. What is presented is a method for weakening the cytokine-induced surface expression of the cell adhesion molecule involving the stage of cell contact to a digoxin antibody composition.EFFECT: group of inventions provides the effective weakening of the cytokine-induced TNF-? surface expression of the ICAM, VCAM and E-selectin molecules due to contacting the cell in need thereof with the digoxin antibody composition.5 cl, 12 dwg, 6 tbl, 4 ex
申请公布号 RU2503463(C2) 申请公布日期 2014.01.10
申请号 RU20090103429 申请日期 2007.07.02
申请人 EHDEJR CHARL'Z DEHVID 发明人 EHDEJR CHARL'Z DEHVID;VAN JUJPIN
分类号 A61K39/395;A61P7/00 主分类号 A61K39/395
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