| 摘要 |
The method for predicting the alterations of liver tissue in the children comprises the assay for TNFα and HGF followed by the calculation of the index of apoptotic-regeneratory reactivity of hepatocytes (IARRH) according to the formula:,whereinIARRH – index of apoptotic-regeneratory reactivity of hepatocytes;TNFα– level of tumor necrosis factor alpha, pmol/L in EDTA-blood plasma;HGF – level of hepatocyte growth factor, pmol/L in EDTA-blood plasma.When IARRH is within 0.85-0.97, the intensities of apoptosis and regeneration of hepatocytes are normal, and the prognosis for function and viability of liver tissue is favorable. When IARRH is within 0.39-0.56, regeneration process is prevailed, and the prognosis for function and viability of liver tissue is conditionally favorable. When IARRH is within 0.971-2.43, apoptosis and degeneration of cells into the connective tissue in hepatitis is evident, and prognosis for function and viability of liver tissue is unfavorable. |
