Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.
申请公布号
AU2012253339(A1)
申请公布日期
2014.01.09
申请号
AU20120253339
申请日期
2012.05.11
申请人
THE REGENTS OF THE UNIVERSITY OF MICHIGAN;SANOFI;WANG, SHAOMENG;SUN, WEI;GARCIA-ECHEVERRIA, CARLOS;AGUILAR, ANGELO
发明人
WANG, SHAOMENG;SUN, WEI;AGUILAR, ANGELO;GARCIA-ECHEVERRIA, CARLOS