发明名称 |
MULTIFUNCTIONAL BIODEGRADABLE PEG NANOCARRIER-BASED HYDROGELS FOR PREVENTING HIV TRANSMISSION |
摘要 |
A multifunctional polyethylene glycol-based hydrogel that includes a multi-arm polyethylene glycol cross-linking unit covalently bound to at least four multi-arm polyethylene glycol nanocarrier units, wherein each nanocarrier unit includes an agent coupled to the nanocarrier unit and each agent is selected from pH-lowering agents, bioadhesion agents, microbicidal-spermicidal agents, and agents that inhibit free and cell-associated HIV binding, provided that each nanocarrier unit comprises a different agent. |
申请公布号 |
US2014010862(A1) |
申请公布日期 |
2014.01.09 |
申请号 |
US201113885681 |
申请日期 |
2011.11.15 |
申请人 |
SINKO PATRICK J.;CHIKINDAS MICHAEL L.;STEIN STANLEY;SINGH YASHVEER;RAJAN SUJATA S.;GAO DAYUAN;NOLL KATIA;RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY |
发明人 |
SINKO PATRICK J.;CHIKINDAS MICHAEL L.;STEIN STANLEY;SINGH YASHVEER;RAJAN SUJATA S.;GAO DAYUAN;NOLL KATIA |
分类号 |
A61K47/48;A61K31/19;A61K38/16 |
主分类号 |
A61K47/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|